| Primary Identifier | MGI:88330 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 12493 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including defense response to protozoan; negative regulation of leukocyte activation; and positive regulation of immunoglobulin production. Predicted to be located in immunological synapse. Predicted to be active in plasma membrane. Is expressed in thymus primordium. Orthologous to human CD37 (CD37 molecule). PHENOTYPE: Homozygous mutation of this gene results in reduced levels of IgG1 immunoglobulins and impaired antibody response to T cell dependent antigens. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
