Primary Identifier | MGI:109375 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 14343 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables galactoside 2-alpha-L-fucosyltransferase activity. Involved in several processes, including fucosylation; olfactory bulb development; and regulation of endothelial cell proliferation. Is active in Golgi apparatus. Orthologous to human FUT1 (fucosyltransferase 1 (H blood group)). PHENOTYPE: Homozygous null mice are viable and healthy, lack alpha(1,2)fucose residues from the apical surface of pancreatic acinar glands and are deficient in epididymal cell surface alpha(1,2)fucosylated glycans but show normal male fertility. [provided by MGI curators] |