| Primary Identifier | MGI:1920706 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 73456 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein binding activity involved in heterotypic cell-cell adhesion; protein homodimerization activity; and receptor ligand activity. Involved in several processes, including binding activity of sperm to zona pellucida; fusion of sperm to egg plasma membrane involved in single fertilization; and syncytium formation by plasma membrane fusion. Located in acrosomal membrane and endoplasmic reticulum membrane. Part of protein complex involved in cell-cell adhesion. Is active in plasma membrane. Orthologous to human IZUMO1 (izumo sperm-oocyte fusion 1). PHENOTYPE: Homozygous null male mice are infertile due to inability of sperm to fuse with the egg. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
