Primary Identifier | MGI:1917153 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 69903 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein homodimerization activity and small GTPase binding activity. Involved in angiogenesis; branching morphogenesis of an epithelial tube; and vasculogenesis. Predicted to be located in Golgi apparatus and perinuclear region of cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cell-cell junction. Is expressed in several structures, including body cavity or lining; cardiovascular system; extraembryonic component; genitourinary system; and vertebral axis musculature. Orthologous to human RASIP1 (Ras interacting protein 1). PHENOTYPE: Mice homozygous for a targeted mutation exhibit complete embryonic lethality during organogenesis associated with a failure in cardiovascular development. [provided by MGI curators] |