Primary Identifier | MGI:109374 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 14344 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables galactoside 2-alpha-L-fucosyltransferase activity. Involved in fucosylation; glycolipid metabolic process; and oligosaccharide biosynthetic process. Acts upstream of or within protein glycosylation. Predicted to be located in Golgi cisterna membrane. Predicted to be active in Golgi apparatus. Is expressed in ileum. Human ortholog(s) of this gene implicated in vitamin B12 deficiency. Orthologous to human FUT2 (fucosyltransferase 2 (H blood group)). PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype. Females are somewhate more susceptible to infections withCandida albicans. [provided by MGI curators] |