Primary Identifier | MGI:1928893 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 56546 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables galactoside 2-alpha-L-fucosyltransferase activity. Involved in oligosaccharide biosynthetic process and protein glycosylation. Predicted to be located in Golgi cisterna membrane. Is expressed in embryo. Human ortholog(s) of this gene implicated in vitamin B12 deficiency. Orthologous to several human genes including FUT2 (fucosyltransferase 2 (H blood group)). PHENOTYPE: Mice homozygous for a null allele exhibit decreased susceptibility to bacterial infection induced morbidity/mortality. [provided by MGI curators] |