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Protein Coding Gene : Sec1 secretory blood group 1

Primary Identifier  MGI:1928893 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  56546
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables galactoside 2-alpha-L-fucosyltransferase activity. Involved in oligosaccharide biosynthetic process and protein glycosylation. Predicted to be located in Golgi cisterna membrane. Is expressed in embryo. Human ortholog(s) of this gene implicated in vitamin B12 deficiency. Orthologous to several human genes including FUT2 (fucosyltransferase 2 (H blood group)).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased susceptibility to bacterial infection induced morbidity/mortality. [provided by MGI curators]
  • synonyms:
  • GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase FUT-III,
  • secretory blood group 1,
  • Sec1,
  • Fut3

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For