Primary Identifier | MGI:94866 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 13170 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within circadian rhythm and regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including extraembryonic component; genitourinary system; limb; liver; and retina layer. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human DBP (D-box binding PAR bZIP transcription factor). PHENOTYPE: Mice homozygous for a null mutation display a shortened circadian period and decreased acvtivity during the dark phase. [provided by MGI curators] |