Primary Identifier | MGI:98221 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 20208 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor binding activity. Acts upstream of or within cholesterol metabolic process and response to bacterium. Located in extracellular space. Is expressed in extraembryonic component; intestine; liver; and placenta. Orthologous to human SAA1 (serum amyloid A1) and SAA2 (serum amyloid A2). PHENOTYPE: Male mice homozygous for a knock-out of SAA1 and SAA2 exhibit increased serum cholesterol in LPS-treated. [provided by MGI curators] |