| Primary Identifier | MGI:3642801 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 629141 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in sperm mitochondrial sheath assembly. Located in mitochondrial outer membrane. Orthologous to human MISFA (mitochondrial sheath formation associated). PHENOTYPE: Mice homozygous for a null allele lacking both the Kastor and Polluks polypeptides exhibit severely reduced male fertility, asthenozoospermia, decreased fertilization frequency, and abnormal sperm mitochondrial sheath morphology. [provided by MGI curators] |