Primary Identifier | MGI:1859271 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 53415 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in import into nucleus and regulation of angiogenesis. Predicted to act upstream of or within positive regulation of programmed cell death; positive regulation of transcription by RNA polymerase II; and protein autophosphorylation. Predicted to be located in cytosol and nuclear envelope. Predicted to be active in cytoplasm. Is expressed in heart and limb. Orthologous to human HTATIP2 (HIV-1 Tat interactive protein 2). PHENOTYPE: Inactivation of this gene increases susceptibility to tumorigenesis. [provided by MGI curators] |