| Primary Identifier | MGI:2181178 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 22652 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Is expressed in gut; nervous system; and sensory organ. Used to study central precocious puberty 2. Human ortholog(s) of this gene implicated in central precocious puberty 2. Orthologous to human MKRN3 (makorin ring finger protein 3). PHENOTYPE: Mice inheriting a null paternal allele exhibit precocious puberty, with earlier preputial separation and vaginal opening, earlier first time of estrus, and increased luteinizing hormone and follicle stimulating hormone serum levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
