Primary Identifier | MGI:95994 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 109815 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATPase binding activity; antioxidant activity; and ubiquitin-specific protease binding activity. Involved in negative regulation of interleukin-6 production and negative regulation of tumor necrosis factor production. Predicted to be located in cytoplasmic microtubule and endoplasmic reticulum membrane. Predicted to be part of endoplasmic reticulum membrane; low-density lipoprotein particle; and very-low-density lipoprotein particle. Is expressed in alimentary system; craniocervical region bone; thoracic segment skeleton; and yolk sac. Orthologous to human SELENOS (selenoprotein S). PHENOTYPE: Mice heterozygous or homozygous for a knock-out allele exhibit impaired contractile function of fast-twitch hindlimb muscles. [provided by MGI curators] |