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Protein Coding Gene : Selenos selenoprotein S

Primary Identifier  MGI:95994 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  109815
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ATPase binding activity; antioxidant activity; and ubiquitin-specific protease binding activity. Involved in negative regulation of interleukin-6 production and negative regulation of tumor necrosis factor production. Predicted to be located in cytoplasmic microtubule and endoplasmic reticulum membrane. Predicted to be part of endoplasmic reticulum membrane; low-density lipoprotein particle; and very-low-density lipoprotein particle. Is expressed in alimentary system; craniocervical region bone; thoracic segment skeleton; and yolk sac. Orthologous to human SELENOS (selenoprotein S).
PHENOTYPE: Mice heterozygous or homozygous for a knock-out allele exhibit impaired contractile function of fast-twitch hindlimb muscles. [provided by MGI curators]
  • synonyms:
  • Vimp,
  • MGD-MRK-10468,
  • histocompatibility 47,
  • H47,
  • MGI:2142327,
  • H4,
  • selenoprotein S,
  • 1500011E07Rik,
  • MGD-MRK-10460,
  • MGD-MRK-10590,
  • MGI:1916234,
  • Seps1,
  • histocompatibility 4,
  • Selenos,
  • expressed sequence C78786,
  • RIKEN cDNA 1500011E07 gene,
  • VCP-interacting membrane protein,
  • H-47,
  • C78786,
  • H-4

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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2 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For