Primary Identifier | MGI:106020 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 20450 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Involved in sialylation. Located in early endosome and recycling endosome. Is expressed in several structures, including central nervous system; eye; future brain; genitourinary system; and gut. Orthologous to human ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2). PHENOTYPE: Homozygous null mice display abnormal mossy fiber morphology, increased exploration in new environment and impaired fear responses. [provided by MGI curators] |