Primary Identifier | MGI:2668031 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 207952 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ubiquitin-like ligase-substrate adaptor activity. Involved in positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; positive regulation of fatty acid oxidation; and ubiquitin-dependent protein catabolic process. Part of Cul3-RING ubiquitin ligase complex. Is expressed in central nervous system; nervous system; peripheral nervous system; and retina. Orthologous to human KLHL25 (kelch like family member 25). PHENOTYPE: Mice harboring an ENU-induced single point mutation show abnormally white teeth. [provided by MGI curators] |