| Primary Identifier | MGI:97385 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 18213 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including GPI-linked ephrin receptor activity; neurotrophin binding activity; and p53 binding activity. Involved in circadian rhythm. Acts upstream of or within several processes, including neurogenesis; neuronal action potential propagation; and positive regulation of nervous system development. Located in cytoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and peripheral nervous system. Human ortholog(s) of this gene implicated in adenoid cystic carcinoma; colorectal cancer; and stomach cancer. Orthologous to human NTRK3 (neurotrophic receptor tyrosine kinase 3). PHENOTYPE: Homozygotes for targeted mutations show a range of phenotypes including postnatal death at 2-21 days, cardiac defects, reduced numbers of dorsal root ganglia neurons and germ cells, abnormal motor coordination and posture and abnormal sensory innervation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
