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Protein Coding Gene : Isg20 interferon-stimulated protein
Primary Identifier  MGI:1928895 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  57444
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable 3'-5' exonuclease activity and RNA binding activity. Predicted to be involved in several processes, including defense response to virus; negative regulation of viral genome replication; and nucleobase-containing compound catabolic process. Predicted to be located in cytoplasm and nuclear lumen. Predicted to be active in nucleus. Is expressed in liver lobe. Orthologous to human ISG20 (interferon stimulated exonuclease gene 20).
PHENOTYPE: Mice with loss of expression in renal tubules display increased susceptibility to kidney reperfusion injury. [provided by MGI curators]
  • synonyms:
  • 20kDa,
  • MGI:1923946,
  • MGI:1914966,
  • Isg20,
  • DnaQl,
  • interferon-stimulated protein,
  • 1600023I01Rik,
  • HEM45,
  • RIKEN cDNA 1600023I01 gene,
  • RIKEN cDNA 2010107M23 gene,
  • 2010107M23Rik
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