| Primary Identifier | MGI:1924261 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 77011 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity. Predicted to be involved in several processes, including DNA metabolic process; mitotic G2/M transition checkpoint; and response to ionizing radiation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in brain. Orthologous to human TICRR (TOPBP1 interacting checkpoint and replication regulator). PHENOTYPE: Mice homozygous for an ENU-induced allele are mostly hairless, with only a light patch of hair around the face and tail. Mice homozygous for a knock-out allele show embryonic lethality before implantation. In vitro outgrowth assays show that embryos fail to hatch from the zona pellucida and die after 3 days in culture, never forming blastocysts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
