Primary Identifier | MGI:1915289 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 68039 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable neuromedin B receptor binding activity and neuropeptide hormone activity. Involved in several processes, including antiviral innate immune response; positive regulation of osteoclast proliferation; and regulation of cytokine production. Located in extracellular space and neuron projection. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in obesity. Orthologous to human NMB (neuromedin B). PHENOTYPE: Mice homozygous for a knockout allele exhibit attenuated scratching in response to histamine, compound 48/80 and 5-HT. [provided by MGI curators] |