Primary Identifier | MGI:3028499 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 269959 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in extracellular matrix. Is expressed in embryo. Orthologous to human ADAMTSL3 (ADAMTS like 3). PHENOTYPE: Mice homozygous for a null allele exhibit increased heart weight, longer tibia bones, and exacerbated cardiac dilatation and contractile dysfunction as well as higher mortality in response to pressure overload. [provided by MGI curators] |