Primary Identifier | MGI:1922806 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 75556 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in flagellated sperm motility. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in several structures, including brain; genitourinary system; lung; node; and sensory organ. Orthologous to human CFAP161 (cilia and flagella associated protein 161). PHENOTYPE: Mice homozygous for one null allele display no phenotypes related to cilia dysfunction. Mice homozygous for a second null allele display enlarged thyroid glands and spleens, and abnormal mouth and mammary gland morphology. [provided by MGI curators] |