| Primary Identifier | MGI:2443629 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 80982 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables hyaluronic acid binding activity and hyalurononglucosaminidase activity. Involved in hyaluronan catabolic process. Located in clathrin-coated vesicle membrane. Is expressed in several structures, including nervous system; retina; and testis. Orthologous to human CEMIP (cell migration inducing hyaluronidase 1). PHENOTYPE: Mice homozygous for a conditional allele activated in Schwann cells exhibit transient acceleration of postnatal myelination, reduced demyelination in culture, and reduced myelin degradation and increases remyelination following nerve axotomy or sciatic nerve crush. Mice homozygous for a null allele exhibit incomplete prenatal lethality, decreased osteoclast cell number, decreased angiogenesis, increased long bone epiphyseal plate size, and short long bones. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
