Primary Identifier | MGI:1919711 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 72461 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metallocarboxypeptidase activity. Involved in angiotensin maturation. Acts upstream of or within several processes, including angiogenesis involved in wound healing; plasma kallikrein-kinin cascade; and regulation of thyroid hormone receptor signaling pathway. Located in basal part of cell and lysosome. Is active in extracellular region. Is expressed in several structures, including axial musculature; brain meninges; craniocervical region bone; foregut; and liver lobe. Orthologous to human PRCP (prolylcarboxypeptidase). PHENOTYPE: Mice homozygous for a gene trap allele exhibit decreased body length, weight, and fat pads with resistance to diet-induced obesity. [provided by MGI curators] |