Primary Identifier | MGI:2682305 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 233532 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone binding activity. Predicted to be involved in several processes, including nucleosome assembly; positive regulation of viral transcription; and regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be part of RSF complex. Is expressed in several structures, including ear; genitourinary system; and nervous system. Orthologous to human RSF1 (remodeling and spacing factor 1). PHENOTYPE: Mice homozygous for a conditional allele activated in neurons exhibit increased susceptibility to etoposide-induced neuron apoptosis with failure to repair double-strand breaks. [provided by MGI curators] |