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Protein Coding Gene : Clns1a chloride channel, nucleotide-sensitive, 1A
Primary Identifier  MGI:109638 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  12729
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in negative regulation of cell volume. Predicted to be located in nucleoplasm. Predicted to be part of methylosome; pICln-Sm protein complex; and spliceosomal complex. Predicted to be active in cytosol. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human CLNS1A (chloride nucleotide-sensitive channel 1A).
PHENOTYPE: Homozygous mutants die between E3.5-E7.5. Heterozygous mutants appear normal and healthy. [provided by MGI curators]
  • synonyms:
  • chloride channel current inducer,
  • Clns1a,
  • RIKEN cDNA 2610036D06 gene,
  • Clci,
  • 2610036D06Rik,
  • 2610100O04Rik,
  • chloride channel, nucleotide-sensitive, 1A,
  • MGD-MRK-39637,
  • ICLN,
  • MGI:1917668,
  • RIKEN cDNA 2610100O04 gene,
  • Clcni,
  • MGI:1919724
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Features --> Cross References

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3 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

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Features --> Overlapping features

Proteins

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Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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