Primary Identifier | MGI:1100859 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 12337 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Located in synapse. Is expressed in several structures, including alimentary system; genitourinary system; immune system; liver and biliary system; and nervous system. Human ortholog(s) of this gene implicated in neovascular inflammatory vitreoretinopathy. Orthologous to human CAPN5 (calpain 5). PHENOTYPE: Mice homozygous for one allele of this gene occasionally exhibit reduced viability but are usually normal. Homozygotes for another allele die as embryos. [provided by MGI curators] |