| Primary Identifier | MGI:2146182 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 106014 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable G protein-coupled receptor binding activity and receptor ligand activity. Acts upstream of or within negative regulation of vascular associated smooth muscle cell proliferation and negative regulation of vascular wound healing. Located in cytoplasm and extracellular region. Is expressed in nervous system. Orthologous to human TAFA5 (TAFA chemokine like family member 5). PHENOTYPE: Homozygous knock-out mice exhibit decreased body weight, increased depressive-like behaviors, impaired spatial learning and memory, reduced glutamate release and neural activity in the hippocampus, and decreased dendritic spine density. [provided by MGI curators] |