Primary Identifier | MGI:2443855 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 244152 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transforming growth factor beta binding activity. Involved in several processes, including cholesterol efflux; cholesterol homeostasis; and neuron projection development. Acts upstream of or within several processes, including ciliary body morphogenesis; negative regulation of Wnt signaling pathway; and telencephalon development. Located in extracellular space. Is expressed in several structures, including olfactory epithelium and skin. Orthologous to human TSKU (tsukushi, small leucine rich proteoglycan). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a failure of anterior commissure axons to cross the midline. [provided by MGI curators] |