Primary Identifier | MGI:1351872 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 101488 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables organic anion transmembrane transporter activity. Predicted to be involved in carboxylic acid transport; sodium-independent organic anion transport; and transmembrane transport. Predicted to be located in basal plasma membrane. Predicted to be active in apical plasma membrane and basolateral plasma membrane. Is expressed in blood vessel; brain meninges; and embryo. Orthologous to human SLCO2B1 (solute carrier organic anion transporter family member 2B1). PHENOTYPE: Mice homozygous for a knock-out allele develop to adulthood normally but show increased blood urea nitrogen level and decreased absorption of fluvastatin, a known SLCO2B1 substrate drug. [provided by MGI curators] |