| Primary Identifier | MGI:1915217 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 67967 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein-macromolecule adaptor activity. Predicted to contribute to DNA-directed DNA polymerase activity. Involved in DNA biosynthetic process. Part of delta DNA polymerase complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human POLD3 (DNA polymerase delta 3, accessory subunit). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality between E4.5 and E7.5 due to failure of proliferation of the inner cell mass and trophoblast giant cells. Mice heterozygous for this allele exhibit age-related decreased male germ cells due to impaired meiosis, shortened telomeres and chromosomal instability. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
