Primary Identifier | MGI:2673874 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 233571 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables G protein-coupled UDP receptor activity. Acts upstream of or within cellular response to organic cyclic compound; cellular response to prostaglandin E stimulus; and transepithelial chloride transport. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in dermomyotome and musculature. Orthologous to human P2RY6 (pyrimidinergic receptor P2Y6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal macrophage, endothelial, and vascular smooth muscle response to UTP and UDP. [provided by MGI curators] |