Primary Identifier | MGI:1920933 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 73683 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in autophagosome assembly. Acts upstream of or within negative stranded viral RNA replication. Located in cytosol and phagophore assembly site membrane. Part of Atg12-Atg5-Atg16 complex. Is expressed in embryo. Orthologous to human ATG16L2 (autophagy related 16 like 2). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit lymphopenia. [provided by MGI curators] |