Primary Identifier | MGI:95569 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 14276 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable folic acid binding activity; folic acid receptor activity; and signaling receptor activity. Predicted to be involved in several processes, including folic acid transport; fusion of sperm to egg plasma membrane involved in single fertilization; and sperm-egg recognition. Predicted to act upstream of or within post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be located in cell surface. Predicted to be active in external side of plasma membrane. Is expressed in brain; extraembryonic component; head; metanephros; and placenta. Orthologous to several human genes including FOLR2 (folate receptor beta). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and physically normal. [provided by MGI curators] |