| Primary Identifier | MGI:1913758 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 66508 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-membrane adaptor activity. Involved in several processes, including lysosome localization; positive regulation of intracellular signal transduction; and regulation of receptor recycling. Is active in lysosomal membrane. Is expressed in several structures, including adipose tissue; alimentary system; early conceptus; nervous system; and reproductive system. Orthologous to human LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit growth arrest and lethality at E7 and abnormal visceral endoderm with abnormal endosome-like organelles and small lysosomes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
