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Protein Coding Gene : Il18bp interleukin 18 binding protein
Primary Identifier  MGI:1333800 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  16068
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable interleukin-18 binding activity. Predicted to be involved in T-helper 1 type immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in gut; liver; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in allergic contact dermatitis and myocardial infarction. Orthologous to human IL18BP (interleukin 18 binding protein).
PHENOTYPE: Homozygous knockout affects NK cell differentiation and function, with an increase in immature cells and a decrease in mature cells. [provided by MGI curators]
  • synonyms:
  • Il18bp,
  • interleukin 18 binding protein,
  • interferon gamma inducing factor binding protein,
  • Igifbp,
  • IL-18BP,
  • MC54L
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0 Exons

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2 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Genes --> Homologs

Interactions

5 Pathways

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Disease

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