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Protein Coding Gene : Trim6 tripartite motif-containing 6

Primary Identifier  MGI:2137352 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  94088
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including negative regulation of viral genome replication; positive regulation of type I interferon-mediated signaling pathway; and regulation of gene expression. Located in cytosol and nucleus. Is expressed in testis. Orthologous to human TRIM6 (tripartite motif containing 6).
PHENOTYPE: Bone marrow-derived dendritic cells and MEFs from homozygous null mice show attenuated recombinant Ebola virus replication. [provided by MGI curators]
  • synonyms:
  • MGI:1924853,
  • DNA segment, Chr 7, ERATO Doi 684, expressed,
  • Trim6,
  • D7Ertd684e,
  • MGI:1289200,
  • tripartite motif-containing 6,
  • C430046K18Rik,
  • RIKEN cDNA C430046K18 gene

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Genome

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0 Exons

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2 Involved In Mutations

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0 Transgenic Expressors

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

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Expression

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Disease

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