Primary Identifier | MGI:2137352 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 94088 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including negative regulation of viral genome replication; positive regulation of type I interferon-mediated signaling pathway; and regulation of gene expression. Located in cytosol and nucleus. Is expressed in testis. Orthologous to human TRIM6 (tripartite motif containing 6). PHENOTYPE: Bone marrow-derived dendritic cells and MEFs from homozygous null mice show attenuated recombinant Ebola virus replication. [provided by MGI curators] |