| Primary Identifier | MGI:1924182 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 76932 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including GTP-dependent protein binding activity; membrane curvature sensor activity; and phosphatidylinositol-4-phosphate binding activity. Predicted to be involved in several processes, including intracellular protein transport; macroautophagy; and regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be located in several cellular components, including Golgi apparatus; nucleolus; and ruffle. Predicted to be active in trans-Golgi network membrane. Orthologous to human ARFIP2 (ARF interacting protein 2). PHENOTYPE: Homozygous null mice exhibit greater diabetic nephropathy following streptozotocin injection, with increased food process effacement, albuminuria, and impaired autophagy but no differences in blood glucose levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
