Primary Identifier | MGI:1926373 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 60510 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SNARE binding activity; identical protein binding activity; and phospholipid binding activity. Involved in calcium-dependent activation of synaptic vesicle fusion and regulation of calcium ion-dependent exocytosis. Located in dense core granule. Is active in hippocampal mossy fiber to CA3 synapse and synaptic vesicle membrane. Is expressed in several structures, including adrenal gland; gonad; liver; nervous system; and spleen. Orthologous to human SYT9 (synaptotagmin 9). PHENOTYPE: Mice homozygous for a null allele exhibit 50% embryonic lethality while cre-mediated removal of a conditional allele impairs inhibitions of postsynaptic currents. [provided by MGI curators] |