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Protein Coding Gene : Dennd2b DENN domain containing 2B
Primary Identifier  MGI:108517 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  76954
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within positive regulation of ERK1 and ERK2 cascade. Predicted to be located in cell cortex; plasma membrane; and recycling endosome. Is expressed in several structures, including brain; future brain; head mesenchyme; heart; and primary palate. Orthologous to human DENND2B (DENN domain containing 2B).
  • synonyms:
  • Dennd2b,
  • MGI:7382744,
  • St5,
  • 2010004M01Rik,
  • 2610305K15Rik,
  • RIKEN cDNA 2010004M01 gene,
  • Denn2b,
  • MGD-MRK-37561,
  • MGI:1924204,
  • RIKEN cDNA 2610305K15 gene,
  • DENN domain containing 2B,
  • MGI:1919751,
  • suppression of tumorigenicity 5,
  • MGI:6369420
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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