| Primary Identifier | MGI:103075 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 22390 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase activity. Acts upstream of or within several processes, including establishment of cell polarity; neuron projection morphogenesis; and peptidyl-tyrosine phosphorylation. Located in cytoplasm. Is expressed in several structures, including brain ventricular layer; early embryo; gut; humerus; and inferior colliculus. Orthologous to human WEE1 (WEE1 G2 checkpoint kinase). PHENOTYPE: Mice homozygous for a transgenic gene disruption may exhibit embryonic lethality at E7. Mice homozygous for a knock-out allele exhibit lethality between E3.5 and E7.5 with reduced proliferation, increased apoptosis and abnormal G2/M checkpoint function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
