| Primary Identifier | MGI:1096344 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 11717 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables AMP deaminase activity. Involved in erythrocyte homeostasis and purine ribonucleotide metabolic process. Acts upstream of or within IMP biosynthetic process and energy homeostasis. Predicted to be active in cytosol. Is expressed in several structures, including heart ventricle; liver; nervous system; placenta; and secondary oocyte. Orthologous to human AMPD3 (adenosine monophosphate deaminase 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased mean corpuscular volume, abnormal erythrocyte physiology including increased erythrocyte ATP levels and osmotic fragility after fasting, and increased lung inflammation after hind-limb ischemia andreperfusion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
