| Primary Identifier | MGI:2136348 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 114332 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cargo receptor activity; hyaluronic acid binding activity; and transmembrane signaling receptor activity. Involved in hyaluronan catabolic process and receptor-mediated endocytosis. Acts upstream of or within glycosaminoglycan catabolic process. Located in plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; hemolymphoid system; meninges; and metanephros. Orthologous to human LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1). PHENOTYPE: Mice homozygous for one allele display enlarged lymphatic vessels and increased interstitial-lymphatic flow. However, mice homozygous for a second allele do not display any abnormalities in the lymphatic system. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
