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Protein Coding Gene : Usp47 ubiquitin specific peptidase 47
Primary Identifier  MGI:1922246 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  74996
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable WD40-repeat domain binding activity and cysteine-type deubiquitinase activity. Involved in cellular response to UV. Acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytosol and nucleus. Orthologous to human USP47 (ubiquitin specific peptidase 47).
PHENOTYPE: Mouse embryonic fibroblasts from mice homozygous for a gene trap allele exhibit increased sensitivity to UV irradiation. [provided by MGI curators]
  • synonyms:
  • Usp47,
  • MGI:2444648,
  • A630020C16Rik,
  • 4930502N04Rik,
  • ubiquitin specific peptidase 47,
  • RIKEN cDNA A630020C16 gene,
  • RIKEN cDNA 4930502N04 gene
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Features --> Cross References

Genome

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0 Exons

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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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