| Primary Identifier | MGI:1917942 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 233752 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable cytoskeletal adaptor activity and protein domain specific binding activity. Predicted to be involved in apical protein localization; regulation of asymmetric cell division; and regulation of protein stability. Predicted to be located in plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in apical cortex. Predicted to colocalize with cell cortex. Is expressed in bone; lung epithelium; metanephros; and nervous system. Orthologous to human INSC (INSC spindle orientation adaptor protein). PHENOTYPE: Homozygous inactivation of this gene leads to abnormal cochlear hair cell morphology. [provided by MGI curators] |