|  Help  |  About  |  Contact Us

Protein Coding Gene : Insc INSC spindle orientation adaptor protein

Primary Identifier  MGI:1917942 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  233752
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Predicted to enable cytoskeletal adaptor activity and protein domain specific binding activity. Predicted to be involved in apical protein localization; regulation of asymmetric cell division; and regulation of protein stability. Predicted to be located in plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in apical cortex. Predicted to colocalize with cell cortex. Is expressed in bone; lung epithelium; metanephros; and nervous system. Orthologous to human INSC (INSC spindle orientation adaptor protein).
PHENOTYPE: Homozygous inactivation of this gene leads to abnormal cochlear hair cell morphology. [provided by MGI curators]
  • synonyms:
  • Insc,
  • RIKEN cDNA 3830422K02 gene,
  • Inscuteable,
  • 3830422K02Rik,
  • INSC spindle orientation adaptor protein

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For