Primary Identifier | MGI:1917942 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 233752 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytoskeletal anchor activity and protein domain specific binding activity. Predicted to be involved in several processes, including apical protein localization; establishment of mitotic spindle orientation; and regulation of asymmetric cell division. Predicted to be located in plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in apical cortex. Predicted to colocalize with cell cortex. Is expressed in bone; lung epithelium; metanephros; and nervous system. Orthologous to human INSC (INSC spindle orientation adaptor protein). PHENOTYPE: Homozygous inactivation of this gene leads to abnormal cochlear hair cell morphology. [provided by MGI curators] |