| Primary Identifier | MGI:1858179 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 53322 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium ion binding activity. Predicted to be involved in several processes, including negative regulation of appetite; negative regulation of cell communication; and positive regulation of testosterone secretion. Predicted to act upstream of or within intracellular calcium ion homeostasis. Located in endoplasmic reticulum and nuclear outer membrane. Is expressed in several structures, including extraembryonic component; female reproductive system; and heart. Orthologous to human NUCB2 (nucleobindin 2). PHENOTYPE: Homozygous mutation of this gene results in decreased heart rate and increased serum alkaline phosphatase levels. Mice homozygous for a null allele exhibit insulin resistance in mice fed a high-fat diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
