| Primary Identifier | MGI:2685341 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 209776 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and neuropeptide receptor activity. Involved in G protein-coupled receptor signaling pathway. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Is expressed in several structures, including ileum; liver; male reproductive gland or organ; nervous system; and spleen. Orthologous to human GPR139 (G protein-coupled receptor 139). PHENOTYPE: Mice homozygous for a knock-out allele exhibit enhanced opioid-induced inhibition of neuronal firing and increased morphine-induced analgesia with augmented reward effects but decreased behavioral withdrawal responses. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
