Primary Identifier | MGI:99538 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 20216 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables medium-chain fatty acid-CoA ligase activity and propionate CoA-transferase activity. Acts upstream of or within fatty acid biosynthetic process. Located in mitochondrial matrix. Is expressed in alimentary system; integumental system; and lower urinary tract. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human ACSM3 (acyl-CoA synthetase medium chain family member 3). PHENOTYPE: Homozygous null mice are viable and fertile with normal kidney function and morphology and blood pressure similar to wild-type on either a regular or high salt diet. [provided by MGI curators] |