| Primary Identifier | MGI:99214 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 22787 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable acrosin binding activity and identical protein binding activity. Predicted to be a structural constituent of egg coat. Involved in binding activity of sperm to zona pellucida and prevention of polyspermy. Located in several cellular components, including collagen-containing extracellular matrix; endoplasmic reticulum; and multivesicular body. Is expressed in germ cell of ovary; oocyte; ovary; secondary oocyte; and testis. Orthologous to human ZP2 (zona pellucida glycoprotein 2). PHENOTYPE: Female homozygous mutants exhibit a thin zona pellucida matrix in early ovarian follicles that becomes disassociated in pre-ovulatory follicles. Few oocytes are produced, and any that are fertilized fail to survive to the two-cell stage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
