Primary Identifier | MGI:1921355 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 74105 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable small GTPase binding activity. Predicted to be involved in Golgi to plasma membrane protein transport and protein localization to cell surface. Predicted to be located in Golgi apparatus and clathrin-coated vesicle. Predicted to be active in trans-Golgi network. Is expressed in several structures, including branchial arch; liver; lung; small intestine; and white fat. Orthologous to human GGA2 (golgi associated, gamma adaptin ear containing, ARF binding protein 2). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit complete embryonic lethality. Mice homozygous for a different gene trapped allele show decreased birth weight, hypoglycemia and partial neonatal lethality, with all remaining mice dying within the first three weeks of life. [provided by MGI curators] |