Primary Identifier | MGI:1353593 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 30949 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein methyltransferase activity. Acts upstream of or within protein methylation and regulation of glucose metabolic process. Located in cytosol. Is expressed in olfactory cortex mantle layer. Orthologous to human LCMT1 (leucine carboxyl methyltransferase 1). PHENOTYPE: Mice homozygous for a gene trap allele are embryonic lethal. Mice homozygous for a hypomorphic gene trap allele exhibit partial embryonic lethality, insulin resistance and impaired glucose tolerance. Mice homozygous for a transgenic gene disruption exhibit kidney agenesis. [provided by MGI curators] |